For academia, individuals, companies, and high school students

Accelerating drug discovery with IT.Closing the gap between experiment and computation.

BaraPhaSilico offers a mentoring program, technology adoption and consulting, collaborative research, science marketing, and a track for high school students.

VALUES

Values

MISSION

Increase the number of Wet × Dry researchers.

VISION

Remove the wall between experiment and computation, and nurture researchers who can generate their own research questions.

CHALLENGES

Does this sound familiar?

  • I want to make experiments more efficient.
  • I want to take on time-consuming, challenging topics — and still build a stronger publication record.
  • I want to keep doing research, even while other work keeps me busy.
Go to Mentoring program

For those who want to introduce in silico drug-discovery methods from the fundamentals.

  • We want to introduce an in silico drug-discovery method beyond those covered in the mentoring program.
  • We want to try a new tool but do not know how to select or implement it.
  • We need a reproducible protocol or how-to video for our laboratory or company.
Go to Technology adoption and consulting

For those who have completed the mentoring program, or already have someone responsible for in silico drug discovery in their company or laboratory.

  • We want to bring in computational science, but we have neither the experience nor someone to own it.
  • We want to bring in current in silico drug discovery methods.
  • We want to turn an in silico drug discovery idea into a real project.
Go to Collaborative research

A plan that builds on the mentoring program and technology adoption and consulting. For those who know what they want to pursue but are unsure how to approach it in silico.

  • We built our own tool, but we want a publication as a track record.
  • There is no researcher in-house, so it is hard to see what to improve.
  • We have no researcher's voice as a user, so we lack material that persuades in the field.
Go to Science marketing

For developers who want their software or tools to reach more researchers.

  • You are aiming for overseas university admissions.
  • You want research experience to show in AO admissions.
  • You want to become a researcher.
Go to Research mentoring for high school students

For high school students who want to build a research track record for overseas or AO admissions, or pursue a future career in research.

NEWS

News

Updates from BaraPhaSilico.

STORY

How BaraPhaSilico began

During my PhD I was a wet-lab researcher. The more time I spent at the bench, the more I felt how long it takes to get even a single result.

Around me, others were struggling too, waiting for results that would not come. It was not a lack of effort. Experiments test hypotheses one by one, and that simply takes time.

After graduating I stepped away from drug discovery for a time, but the wish to keep working on it did not change. I taught myself in silico methods and used the computer to narrow hypotheses. With the help of my collaborators, I was able to write the work up as a paper about six months after starting the project.

Learning dry methods makes it possible to examine a hypothesis before going to the bench, and to look at experimental data from another angle. Dry work does not only support wet research; it can produce results of its own, and the range of what a researcher can do grows.

I wanted to bring this experience to researchers who, like me, were unsure how to move their work forward. That wish became BaraPhaSilico.

We understand the reality of experimental research, and from there we support data analysis, hands-on in silico drug discovery, and the learning of new techniques. We walk alongside researchers as they combine their own expertise with new methods and take the work forward.

By bringing AI and IT together with a broad view of drug discovery, we hope to shorten the time it takes to find a medicine, and to help one more medicine reach the people who need it.

FOUNDER

Founder

Koki Shinbara, founder of BaraPhaSilico

Koki Shimbara

新原 光貴

Founder, BaraPhaSilico / Ph.D. in Science / Bioinformatician at a global life-science company / Visiting faculty, Hokkaido University vaccine R&D hub

Shizuku iconしずく@shizuku50312776

At Tokyo University of Science (Faculty of Pharmaceutical Sciences) and the University of Tokyo (Graduate School of Science), he worked on peptide screening, small-molecule chemistry, peptide synthesis and biochemical assays.

After graduating, he learned DX and IT at an IT startup, then worked as a bioinformatician at a global life-science instrument vendor.

Wanting wet-lab researchers to take up dry research, he founded BaraPhaSilico.

CONTACT

Contact / free first consultation

Enquiries about the mentoring program, technology adoption and consulting, collaborative research, science marketing, and the high-school track are welcome. We usually reply within 2–3 business days.