For academia, individuals, companies, and high school students

Accelerating drug discovery with IT.Closing the gap between experiment and computation.

BaraPhaSilico offers a mentoring program, technology adoption and consulting, collaborative research, science marketing, and a track for high school students.

VALUES

Values

MISSION

Increase the number of Wet × Dry researchers.

VISION

Remove the wall between experiment and computation, and nurture researchers who can generate their own research questions.

CHALLENGES

Does this sound familiar?

  • We want to bring in computational science, but we have neither the experience nor someone to own it.
  • We want to bring in current in silico drug discovery methods.
  • We want to turn an in silico drug discovery idea into a real project.

SERVICES

Five services

With experience on both the wet and dry side of drug discovery, we support researchers, institutions, companies and high school students in the way that fits each of them.

Popular

Wet × Dry researcher training through to publication

Mentoring program

For those who want to introduce in silico drug-discovery methods from the fundamentals.

From setting up a research environment and Python, to in silico drug discovery (docking, virtual screening, MD), research design and publication strategy. You do the hands-on work; we mentor you until the paper is written.

  • Fully online, unlimited questions
  • Built around your own research topic
  • Limited to 4 participants per year
Program details

Technology adoption and consulting

For those who have completed the mentoring program, or already have someone responsible for in silico drug discovery in their company or laboratory.

For people who want to add methods beyond the tools covered in the mentoring program. Each plan is sized for introducing about one tool.

  • Plan A: question and tool recommendation (JPY 50,000 / month)
  • Plan B (recommended): implementation, protocol and video (JPY 100,000 / month)
  • Plan C: exclusive protocol, not disclosed (JPY 200,000 / month)
Learn more

Collaborative research

A plan that builds on the mentoring program and technology adoption and consulting. For those who know what they want to pursue but are unsure how to approach it in silico.

For people who want to do collaborative research with BaraPhaSilico.

  • Want computational science, but lack the experience and a person to own it
  • Want current in silico drug discovery methods
  • Want to turn an in silico drug discovery idea into a real project
Learn more

For companies

Science marketing

For developers who want their software or tools to reach more researchers.

We use your product or service in real drug-discovery research and publish the results as a paper. You receive a track record in the literature and an authentic researcher's voice as marketing material.

  • Publication as a case study of adoption
  • A usage report from a researcher's point of view
  • Outreach via technical books, blog and video
Learn more

Overseas admissions, AO admissions, future researchers

Research mentoring for high school students

For high school students who want to build a research track record for overseas or AO admissions, or pursue a future career in research.

Our founder holds a Ph.D. in science from the University of Tokyo, is a faculty member at one of Japan's former Imperial Universities, and has worked in both computational and experimental science. He works with each student's goals and character, and designs an in silico drug-discovery research plan and admissions support through conversation.

  • For overseas admissions, AO admissions, and students who want to become researchers
  • Focus on visible outcomes: research presentations and publication
  • We do the research together, as a mentor
Learn more

STORY

How BaraPhaSilico began

During my PhD I was a wet-lab researcher. The more time I spent at the bench, the more I felt how long it takes to get even a single result.

Around me, others were struggling too, waiting for results that would not come. It was not a lack of effort. Experiments test hypotheses one by one, and that simply takes time.

After graduating I stepped away from drug discovery for a time, but the wish to keep working on it did not change. I taught myself in silico methods and used the computer to narrow hypotheses. With the help of my collaborators, I was able to write the work up as a paper about six months after starting the project.

Learning dry methods makes it possible to examine a hypothesis before going to the bench, and to look at experimental data from another angle. Dry work does not only support wet research; it can produce results of its own, and the range of what a researcher can do grows.

I wanted to bring this experience to researchers who, like me, were unsure how to move their work forward. That wish became BaraPhaSilico.

We understand the reality of experimental research, and from there we support data analysis, hands-on in silico drug discovery, and the learning of new techniques. We walk alongside researchers as they combine their own expertise with new methods and take the work forward.

By bringing AI and IT together with a broad view of drug discovery, we hope to shorten the time it takes to find a medicine, and to help one more medicine reach the people who need it.

FOUNDER

Founder

Koki Shinbara, founder of BaraPhaSilico

Koki Shimbara

新原 光貴

Founder, BaraPhaSilico / Ph.D. in Science / Bioinformatician at a global life-science company / Visiting faculty, Hokkaido University vaccine R&D hub

Shizuku iconしずく@shizuku50312776

At Tokyo University of Science (Faculty of Pharmaceutical Sciences) and the University of Tokyo (Graduate School of Science), he worked on peptide screening, small-molecule chemistry, peptide synthesis and biochemical assays.

After graduating, he learned DX and IT at an IT startup, then worked as a bioinformatician at a global life-science instrument vendor.

Wanting wet-lab researchers to take up dry research, he founded BaraPhaSilico.

CONTACT

Contact / free first consultation

Enquiries about the mentoring program, technology adoption and consulting, collaborative research, science marketing, and the high-school track are welcome. We usually reply within 2–3 business days.